The output of kextstat indicates that you have the Apple USB CDC driver (good) and the WCH custom driver (bad) installed.
The USB CDC driver implements the USB-to-Serial protocol as defined by the USB standard. This protocol is used by the auxiliary ATMEL MEGA16U2 chip on the Arduino Uno board.
The WCH driver is from the Chinese manufacturer of the CH340G USB-to-serial chip. It is often found on ESP32 boards. I recommend to uninstall this driver as newer macOS versions come with an Apple driver for this chip (driver is found at /System/Library/DriverExtensions/DriverKit.AppleUSBCHCOM.dext).
For the uninstallation, see: