Error: libusb_open() failed when trying to debug

YES YES YES !!! - something happened. I would mark this as solution solved if I knew how… !!! I cannot describe how glad I am for your eminent world class support - for three problems up till now.

First I deleted the device and I was asked if I wanted to remove the driver. Yes - I did that. Then I reinstalled the driver (twice - the first try was not succesfull) and ran the project again. Now - the “libusb_open() failed with LIBUSB_ERROR_NOT_SUPPORTED” is still there - BUT - suddenly debugging works.

When I start the project the debugging messages are:
Info : tcl server disabled
Info : telnet server disabled
Error: libusb_open() failed with LIBUSB_ERROR_NOT_SUPPORTED
Info : clock speed 5000 kHz
Info : JTAG tap: esp32.cpu0 tap/device found: 0x120034e5 (mfg: 0x272 (Tensilica), part: 0x2003, ver: 0x1)
Info : JTAG tap: esp32.cpu1 tap/device found: 0x120034e5 (mfg: 0x272 (Tensilica), part: 0x2003, ver: 0x1)
Info : esp32.cpu0: Detected debug stubs @ 3ffb41e4
Info : accepting ‘gdb’ connection from pipe
Warn : No symbols for FreeRTOS!
Info : esp32.cpu0: Target halted, PC=0x4013FCDE, debug_reason=00000000
Info : Set GDB target to ‘esp32.cpu0’… etc…

May I ask:
Info : JTAG tap: esp32.cpu0 tap/device found: 0x120034e5 (mfg: 0x272 (Tensilica), part: 0x2003, ver: 0x1)
Info : JTAG tap: esp32.cpu1 tap/device found: 0x120034e5 (mfg: 0x272 (Tensilica), part: 0x2003, ver: 0x1)

Should the interface 1 only connect as a comport?