I just run the copy of pioplus.exe I have on my machine
And this was the result - no matches at all across 70 different AV engines.
If you want to see if there is something going on on your system, load the file you have onto VirusTotal, and see if it gives the same results/matches as the the scan I did.
And like Max said, packing can be a common cause of false positives… I found out the other day that AV scanners are starting to blindly go “that UPX compressed executable must be a virus”… even though that UPX compressed executable was the self-contained version of some code I had written and compiled! Oh how I hate how lazy these AV vendors are becoming!