So far I have no experience with debug output via USBSerial and would have to have a look / try it out. Unfortunately, I’m traveling all day today and can’t get to my ESP32-S3 board.
Please note that not only ARDUINO_USB_CDC_ON_BOOT but the combination of ARDUINO_USB_MODE is crucial! See ESP32-S3 native USB interface and Serial Monitor missing first messages - #10 by sivar2311