Hi thanks for fast responding. I tried every option in zadig. 3 of them ended in the same issue of timeout and the other USB Serial (CDC) could not find the jlink.
I checked the wires carefully and get same connections with the topic ESP32 + Jlink debugger does not start. Only nTRST is not aviable and therefore EN is connected to nReset as mentioned above.
On the ESP32 board there are some components for the arduino ide to upload some code. I desolderet the components U2, VT1 and VT2 just to get sure nothing makes problems with the jlink. You find the schematic here.