Adafruit NeoTrellis M4

That is the most basic thing that should work. Can you try a minimal firmware

#include <Arduino.h>

void setup() {
    Serial.begin(115200);
}

void loop() {
   static int i = 0;
   i++;
   Serial.println("Test " + String(i));
   delay(1000);
}

? Maybe needs monitor_speed = 115200 in the platformio.ini. Is there no output?